Misclassification does not explain increased cardiovascular risks of calcium supplements
نویسندگان
چکیده
منابع مشابه
Calcium supplements: benefits and risks.
Calcium is an essential element in the diet, but there is continuing controversy regarding its optimal intake, and its role in the pathogenesis of osteoporosis. Most studies show little evidence of a relationship between calcium intake and bone density, or the rate of bone loss. Re-analysis of data from the placebo group from the Auckland Calcium Study demonstrates no relationship between dieta...
متن کاملCardiovascular Effects of Calcium Supplements
Calcium supplements reduce bone turnover and slow the rate of bone loss. However, few studies have demonstrated reduced fracture incidence with calcium supplements, and meta-analyses show only a 10% decrease in fractures, which is of borderline statistical and clinical significance. Trials in normal older women and in patients with renal impairment suggest that calcium supplements increase the ...
متن کاملDoes hypoadiponectinemia explain the increased risk of diabetes and cardiovascular disease in South Asians?
A substantial body of evidence has documented the high prevalence of type 2 diabetes and cardiovascular disease (CVD) among people of SouthAsian descent, defined on the basis of ancestral origin from the Indian subcontinent comprised of India, Pakistan, Bangladesh, and Sri Lanka (1–7). These observations relate to both native South Asians in urban settings and those living overseas in different...
متن کاملCalcium supplementation: balancing the cardiovascular risks.
Calcium supplementation has been widely accepted as a key strategy in the prevention and treatment of osteoporosis. Its role has been undermined, to some extent, by its disappointing effects on fracture in randomised controlled trials, but its use has continued to be encouraged on the grounds that it is physiologically appealing, and is unlikely to cause harm. The latter assumption is now under...
متن کاملAltered Calcium Homeostasis Does Not Explain the Contractile Deficit of Diabetic Cardiomyopathy
OBJECTIVE This study examines the extent to which the contractile deficit of diabetic cardiomyopathy is due to altered Ca(2+) homeostasis. RESEARCH DESIGN AND METHODS Measurements of isometric force and intracellular calcium ([Ca(2+)](i), using fura-2/AM) were made in left ventricular (LV) trabeculae from rats with streptozotocin-induced diabetes and age-matched siblings. RESULTS At 1.5 mmo...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2012
ISSN: 0884-0431
DOI: 10.1002/jbmr.1568